Cellular physiological properties are closely related to the biological, chemical and physical properties of cells. The patch clamp technique is a laboratory technique in electrophysiology, which is used to study ionic currents in individual isolated living cells, tissue sections, or patches of cell membrane, investigating cellular physiological functions. The development of the patch-clamp technique has given electrophysiologists new prospects. It allows high-resolution current recordings not only of whole cells, but also of excised cellular patches.