Global Run-On Sequencing (GRO-Seq), also known as Nascent RNA Sequencing Analysis (NRSA), is a next-generation sequencing (NGS)-based method to detect transcripts that are initiated at the time of nuclei isolation (commonly referred to as nascent RNA). In a GRO-Seq protocol, nascent RNA is isolated and can be ultimately converted into a DNA library suitable for deep sequencing. We provide comprehensive GRO-Seq services to help you identify nascent transcription changes for genes and enhancers.