SOST is a secreted glycoprotein that is mainly expressed by osteocytes as a negative regulator of bone formation. SOST is a marker of mature osteocytes, and its expression gradually increases as osteocytes mature and acquire intact molecular features. SOST plays an important role in bone homeostasis, and lack of SOST causes increase bone formation, leads to high bone mass human syndrome Van Buchem disease and sclerost
eosis. Creative BioMart Biomarker is capable to provide our customers with superior SOST detection service, various detection methods ensuring high sensitivity for detecting biomarkers in different samples with different concentrations.