The Absolute Mag™ Lanthanide-Based Magnetic Particles is a kind of super-paramagnetic magnetic particles formed by the reaction of a strong lanthanide element (Ln) mono-electronic oxidant with Massart magnetite under high-power ultrasonic irradiation. These particles have a γ-Fe2O3 core and are positively charged, hydrophilic, and not easy to aggregate in aqueous suspensions/ferrofluids due to electrostatic repulsion. Since the lanthanide elements have a characteristic oxidation state of +3 valence, it is readily reacts with the Lewis base, therefore, the particles can also be further functionalization.