PDE-5 is an enzyme that delays erectile opera operative, preserving the effect once in an improved erectile function. The ED medicine enables the sexually aroused men to attain a stronger erection which is hard . enough to penetrate. The effect stays active for 48 hours. At the same time the tensions open which increases the blood flow to the man organ for communication. tadalista component in the drug is a clinically proven impotence drug that inhibits the secretion of PDE5 enzyme. It is mainly used to treat erectile dysfunction in men, but has so far been known to cause some rare side effects such as headache, flushing, abdominal discomfort, diarrhea and dizziness. Inform your doctor immediately if these effects persist or degrade. For a person with cardiac problems, the side effects of this drug can be severe. Before buying any incapability pills, it is advisable to consult a doctor and make a judgment, if artificial drugs are the best treatment for you. The required dose of mg is prescribed approximately 1 hour before sexual activity. The most important characteristic of this molecule is a long lasting effect, which can last up to 36 hours, as well as the fact of the concentration of the drug.