Painful spider veins on legs can cause burning, itching, throbbing, or sensitivity, especially after long periods of standing. Fortunately, several non-surgical treatment options are available. Sclerotherapy is one of the most common approaches, involving a medical solution injected into the affected veins to help them collapse and gradually fade. Laser-based treatments may also be used for smaller surface veins. These minimally invasive procedures are typically performed in outpatient settings with little downtime. Clinics such as USA Vein Clinics provide ultrasound-guided evaluations to determine the underlying cause and recommend personalized treatment for painful spider veins.