Different Trials will pop up in every node. Here's a detailed list of them and what to do in each case:
Chalice Trial: Defeat the Two Boss Monsters. Approach the Chalice and follow the blood path to find them.
Escape Trial (timed): Defuse every Death Crystal before the time runs out. Follow the path marked upon, deactivating each crystal to find the next one. Avoid monsters to Path of exile currency prevent running out of time. If time runs out, players will immediately fail the whole Trial and have to start over.
Gauntlet Trial: Avoid traps, find the levers, and escape the room. Players will have to do this, as they prevent damage from traps, as this will chip away at their honor pool.
Hourglass Trial (timed): Activate the hourglass and survive waves of enemies until the time runs out. It is not obligatory to kill the monsters, but they will drop Sacred Water, so it's up to the challenger to decide what to do.
Ritual Trial: Find the Summoners opening portals, then kill them and the beasts they summon to deactivate the portals. Repeat until completing the Trial.
Boss Trial: The players will face the following boss at the end of each floor (Tier) in the Trials: Tier 1 - Rattlecage, the Earthbreaker; Tier 2 - Terracotta Sentinels; Tier 3 - Ashar, the Sand Mother; and Tier 4 - Zarokh, the Temporal.
To complete the Trials of the Sekhemas and attain Ascension, players will have to balance out these and choose the safest path that helps them preserve Honor, preventing certain Curses that can greatly decrease their chances of completing the Trials. A boss named Rattlecage, the Earthbreaker awaits at the end of several sections, and they are quite complicated.
The most straightforward way to win against him is to bring Fire Resistance in the form of Charms, Rings, and any boon that increases the mentioned Elemental Resistance in all the pieces of equipment players can get their hands on.
Then, avoid the lava cracks he summons, and bring him down by POE currency for sale stunning him. Rinse and repeat to complete this tiresome battle and attain ascension.