2. Kurast Undercity Runs (With Tribute of Harmony)
The Kurast Undercity is a new repeatable endgame feature where you earn rewards for Diablo 4 Items completing timed runs. Using Tributes lets you target specific rewards.
Tribute of Harmony: Guarantees Runes upon completion of a successful run.
Kurast Undercity runs are ideal for both Rune farming and character progression, with a high chance to earn high-tier Runes when using the right Tribute.
3. World Bosses and the Hatred Rising Event (Realm walkers)
World Bosses still spawn every week and drop valuable rewards, including Runes.
Realmwalkers, new bosses introduced in Season 6, can be farmed repeatedly.
Realmwalkers appear throughout Sanctuary, wandering through zones and summoning waves of enemies.
Defeating them or their minions in the Seething Realm offers frequent Rune drops, making them a key target for Rune farming.
4. Clear Strongholds for the First Time
Each Stronghold completed for Diablo 4 Items for sale the first time grants significant XP and items, with a high chance of Rune rewards.
Strongholds reset for every season and character, meaning even if you’ve cleared them before, your Season 6 character can do so again for Runes.