| ASOs-based lncRNA knockdown | IntegrateRNA provides customers with a proven, cost-effective, and simple way to perform post-transcriptional silencing of lncRNAs. We utilize locked nucleic acid (LNA) modified siRNAs to silence the lncRNA located in the cytoplasm and LNA-enhanced antisense oligonucleotides (ASOs) to silence the lncRNA located in the nucleus and cytoplasm. Our services enable you systematically analyze the function of lncRNA in vivo and in vitro, especially in a wide range of model systems. Besides, we use optimized and upgraded algorithms for site screening and experimental design to ensure efficient silencing and reduce off-target effects. |