| structure of siliac acid | Sialic acids are negatively charged monosaccharides, what are found on the non-reducing termini of glycans. The key role in product stability and efficacy, thus, sialic acids are often defined in glycoprotein therapeutic products. There exist two most common sialic acids in biopharmaceuticals, the one is N-acetyl-neuraminic acid (Neu5Ac) and the other one is N-glycolyl-neuraminic acid (Neu5Gc). The sialic acid mentioned above are both important to the firmness and 3D conformation of glycoproteins, they are involved in many biological interactions. |