Interactions between biological macromolecules regulate various biological processes. Many molecular biology and biochemistry methods have been developed to detect this interaction, such as pull-down assay, co-immunoprecipitation (Co-IP), yeast two-hybrid analysis, surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC). However, fluorescence resonance energy transfer (FRET) technology has gained great popularity due to its ability to detect interactions with extremely high spatiotemporal resolution in physiological conditions in a non-invasive manner. As an expert in structural biology and protein research, Creative Biostructure is helping our customers with diverse basic and preclinical research services targeting coronavirus infections, including COVID-19. We offer FRET technology-based assay development and detection services for coronavirus research.