2230821-27-7

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asked Apr 20, 2022 in H&E by bocsci119 (2,100 points)

2230821-27-7

Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R).

 

 

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