The outbreak of novel coronavirus (SARS-CoV-2, formerly known as 2019-nCoV) has drawn global attention, prompting the urgent need to find specific and broad-spectrum antiviral drugs. With years of experience in structure-based drug design (SBDD), Creative Biostructure combines multidisciplinary drug discovery expertise to provide lead optimization services for coronavirus infection to support the discovery of effective preclinical antiviral drug candidates.