Vaccine development is a long and complicated process, always requiring over ten years. Vaccines can be prophylactic or therapeutic. A prophylactic vaccine is to prevent a future infection by a natural pathogen, while a therapeutic vaccine is always against cancer. Vaccines are often dead or inactivated native pathogen or pathogen analog. Here, we give a brief introduction to the applications of exosomes in vaccine development. Besides, to aid in exosome research, Creative Biolabs is offering a comprehensive array of exosome-related services to help the vaccine development.