2209085-22-1

0 votes
asked Jan 24, 2022 in Cell Tracking by bocsci119 (2,100 points)

2209085-22-1

JH-XI-10-02 is a potent and selective degrader of CDK8, with an IC50 of 159 nM, based on PROTAC. JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02 shows no effect on CDK19.

 

 

Please log in or register to answer this question.

Welcome to Bioimagingcore Q&A, where you can ask questions and receive answers from other members of the community.
...