Proteins are highly adaptable and can evolve novel functions and structures. In fact, examples of the evolutionary fitness of proteins can be found everywhere, such as the numerous proteins originating from a common ancestor in nature, as well as drug resistance mechanisms caused by drug abuse, that is, the generation of various drug-resistant enzymes. Creative Biostructure supports the evolutionary analysis of coronavirus-related proteins through bioinformatics methods to help you understand the impact of local active sites on function, the overall conformational diversity of proteins, and the rate of protein evolution.