〡Characteristics
2-Hydroxypropyl-β-cyclodextrin is the most widely used modified cyclodextrin.It has shown to change the physicochemical properties of lipophilic compounds when co-administered. It has the best balance of enhanced aqueous solubility, a wide range of drugs with which it forms stable complexes, and the most extensive collection of safety data in the technical literature with no adverse reactions reported.It is very soluble in water.
〡Applications
2-hydroxypropyl-β-cyclodextrin is an ideal injection solubilizer and drug excipient. It can improve the water solubility of insoluble drugs, increase the stability of drugs, improve the bioavailability of drugs, increase the curative effect of drugs or reduce the dosage. It can adjust or control the release rate of drugs and reduce the side effects of drugs.
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