(2-Hydroxypropyl)-γ-cyclodextrin, HPGCD is a gamma cyclodextrin that is a derivative of an 8-membered sugar ring molecule. (2-Hydroxypropyl)-γ-cyclodextrin can crosslink to form longer polymers. This overall is a very useful chemical for supramolecular chemistry. (2-Hydroxypropyl)-γ-cyclodextrin is also used in the solubilization of macromolecules and in cell culture applications. (2-Hydroxypropyl)-γ-cyclodextrin is similar to β-Cyclodextrin (sc-204430), but (2-Hydroxypropyl)-γ-cyclodextrin can work with larger molecules.
Hydroxypropyl Gamma cyclodextrin is recommended for high value-added special materials products, such as medicine, health care products, cosmetics or other larger molecularor which hydroxypropyl beta cyclodextrin has no ability to treat.
HPGCD's water solubility increase to 80g/100ml (25 C) furtherly , and hydroxypropyl gamma cyclodextrin is no longer a single pure compound but a coexistence of multiple substituted compounds, when including with guest molecules is not easy to generate crystallization. Overall, hydroxypropyl- gamma cyclodextrin has a higher solubility in water and stronger anti crystallization ability.
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