Pomalidomide-PEG2-Alkyne

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asked Aug 31, 2021 in H&E by bocsci118 (7,960 points)

Pomalidomide-PEG2-Alkyne

Pomalidomide-PEG2-Alkyne is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal alkyne for click chemistry with an azide on the target ligand. It has been used as a degrader buildin

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