The P53 Probe uses orange-red dye to mark the P53 gene region, and the green dye to mark the centromeric region of chromosome 17 (CEP17). The P53 gene tagged region is located at 17q13.1, and the CEP17 probe is labeled with a specific alpha satellite sequence.
P53 Probe
â—†Clinical Significance
The amplification and deletion of P53 gene indicate the poor prognosis of the tumor, it is insensitive to conventional chemotherapy, and the tumor is susceptible to metastasis.
https://www.health-carebiotech.com/molecular-diagnostic-probe/fluorescence-in-situ-hybridization-probes/p53-probe.html