Unlike Nerve renew non- painkillers, no ceiling effect of drugs. Dose effect increases with increasing pain until unconsciousness develops. are used for severe pain. drugs have the potential to addiction. The dependency of drugs, many physicians because of the fear of severe pain in patients with unrelenting pain and other drugs are prescribed, even avoids. Adequate pain management of patients with cancer pain is one of the most important reasons. However, studies in patients with Blood sugar formula addiction to drugs shown to be very low risk.